Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes
In Ecuador, the use of organophosphorus pesticides in agriculture has become a public health problem, according to bibliographic data, people exposed to these agrochemicals in occupational ways show alterations in their health. This study was focused on the assessment of hematological and morphologi...
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| Format: | Online |
| Language: | spa |
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Universidad Pedagógica y Tecnológica de Colombia
2020
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| Online Access: | https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/10603 |
| _version_ | 1801706476939509760 |
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| author | Esparza-Olalla, Johanna Elizabeth Forero-Lugo, Francy Carolina Mardones-Montanares, Marcela Alejandra |
| author_facet | Esparza-Olalla, Johanna Elizabeth Forero-Lugo, Francy Carolina Mardones-Montanares, Marcela Alejandra |
| author_sort | Esparza-Olalla, Johanna Elizabeth |
| collection | OJS |
| description | In Ecuador, the use of organophosphorus pesticides in agriculture has become a public health problem, according to bibliographic data, people exposed to these agrochemicals in occupational ways show alterations in their health. This study was focused on the assessment of hematological and morphological parameters of farmers exposed in an occupational way to these pesticides. It is an observational, descriptive cross-sectional and correlational study. In the community of Guaslán-Ecuador approximately 400 people are engaged in agriculture, of which 186 individuals were part of the study freely and voluntarily. 53% of the population were women, 47% men. The assessment of the blood count allowed to determine quantitative alterations such as: polyglobulia, leukocytosis, neutrophilia, lymphocytosis and platelet changes. Cellular morphology was assessed with the analysis of the peripheral blood smear that showed qualitative alterations in red, white and platelet cells. The most relevant findings were: neutrophils with toxic granulation, reactive lymphocytes, hypersegmentation, large platelets and stomatocytosis. Erythrocyte cholinesterase obtained 13% of the population. The 99% of the population presented at least one quantitative alteration and 80% qualitative alterations. Cholinesterase activity was inversely proportional to the exposure time. It is concluded that organophosphorus pesticides are capable of producing alterations at the cellular and enzymatic level. It is recommended to include the blood count and peripheral blood smear as markers of hemotoxicity in occupational tests or epidemiological profile for people exposed to this type of agrochemicals. |
| format | Online |
| id | oai:oai.revistas.uptc.edu.co:article-10603 |
| institution | Revista Ciencia y Agricultura |
| language | spa |
| publishDate | 2020 |
| publisher | Universidad Pedagógica y Tecnológica de Colombia |
| record_format | ojs |
| spelling | oai:oai.revistas.uptc.edu.co:article-106032021-07-13T04:49:56Z Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes Uso de organofosforados por agricultores de la comunidad de Guaslán- Ecuador y los cambios hematológicos Esparza-Olalla, Johanna Elizabeth Forero-Lugo, Francy Carolina Mardones-Montanares, Marcela Alejandra blood count cholinesterase farmers organophosphorus public health agricultores colinesterasa hemograma organofosforados salud pública In Ecuador, the use of organophosphorus pesticides in agriculture has become a public health problem, according to bibliographic data, people exposed to these agrochemicals in occupational ways show alterations in their health. This study was focused on the assessment of hematological and morphological parameters of farmers exposed in an occupational way to these pesticides. It is an observational, descriptive cross-sectional and correlational study. In the community of Guaslán-Ecuador approximately 400 people are engaged in agriculture, of which 186 individuals were part of the study freely and voluntarily. 53% of the population were women, 47% men. The assessment of the blood count allowed to determine quantitative alterations such as: polyglobulia, leukocytosis, neutrophilia, lymphocytosis and platelet changes. Cellular morphology was assessed with the analysis of the peripheral blood smear that showed qualitative alterations in red, white and platelet cells. The most relevant findings were: neutrophils with toxic granulation, reactive lymphocytes, hypersegmentation, large platelets and stomatocytosis. Erythrocyte cholinesterase obtained 13% of the population. The 99% of the population presented at least one quantitative alteration and 80% qualitative alterations. Cholinesterase activity was inversely proportional to the exposure time. It is concluded that organophosphorus pesticides are capable of producing alterations at the cellular and enzymatic level. It is recommended to include the blood count and peripheral blood smear as markers of hemotoxicity in occupational tests or epidemiological profile for people exposed to this type of agrochemicals. En Ecuador el uso de plaguicidas organofosforados en la agricultura se ha convertido en un problema de salud pública, según datos bibliográficos las personas expuestas de manera ocupacional a estos agroquímicos manifiestan alteraciones en su salud. Este estudio fue enfocado en la valoración de parámetros hematológicos y morfológicos de agricultores expuestos de forma ocupacional a estos plaguicidas. Es un estudio observacional, descriptivo de corte transversal y correlacional. En la comunidad de Guaslán-Ecuador aproximadamente 400 personas se dedican a la agricultura, de los cuales 186 individuos formaron parte del estudio forma libre y voluntaria. El 53% de la población fueron mujeres, el 47% hombres. La valoración del hemograma permitió determinar alteraciones cuantitativas como: poliglobulia, leucocitosis, neutrofilia, linfocitosis y cambios en las plaquetas. La morfología celular se valoró con el análisis del frotis de sangre periférica que evidenció alteraciones cualitativas en glóbulos rojos, blancos y plaquetas. Los hallazgos más relevantes fueron: neutrófilos con granulación tóxica, linfocitos reactivos, hipersegmentación, plaquetas grandes y estomatocitosis. La colinesterasa eritrocitaria obtuvo 13% de la población. El 99% de la población presentó al menos una alteración cuantitativa y un 80% alteraciones cualitativas. La actividad de la colinesterasa resultó inversamente proporcional al tiempo de exposición. Se concluye que los plaguicidas organofosforados son capaces de producir alteraciones a nivel celular y enzimático. Se recomienda incluir el hemograma y el frotis de sangre periférica como marcadores de hemotoxicidad en pruebas ocupacionales o de perfil epidemiológico para personas expuestas a este tipo de agroquímicos. Universidad Pedagógica y Tecnológica de Colombia 2020-02-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion research investigación application/pdf application/xml https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/10603 10.19053/01228420.v17.n1.2020.10603 Ciencia y Agricultura; Vol. 17 No. 1 (2020): January-April 2020; 31-50 Ciencia y Agricultura; Vol. 17 Núm. 1 (2020): Enero-Abril 2020; 31-50 2539-0899 spa https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/10603/8774 https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/10603/8945 N.A. N.A. |
| spellingShingle | blood count cholinesterase farmers organophosphorus public health agricultores colinesterasa hemograma organofosforados salud pública Esparza-Olalla, Johanna Elizabeth Forero-Lugo, Francy Carolina Mardones-Montanares, Marcela Alejandra Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes |
| title | Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes |
| title_alt | Uso de organofosforados por agricultores de la comunidad de Guaslán- Ecuador y los cambios hematológicos |
| title_full | Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes |
| title_fullStr | Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes |
| title_full_unstemmed | Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes |
| title_short | Use of organophosphates by farmers in the community of Guaslán- Ecuador and hematological changes |
| title_sort | use of organophosphates by farmers in the community of guaslan ecuador and hematological changes |
| topic | blood count cholinesterase farmers organophosphorus public health agricultores colinesterasa hemograma organofosforados salud pública |
| topic_facet | blood count cholinesterase farmers organophosphorus public health agricultores colinesterasa hemograma organofosforados salud pública |
| url | https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/10603 |
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