Tota Lake Pollution and Biological Models for Genotoxicity Studies
Tota Lake is a water source of great importance at a regional and national level given its environmental and economic value, the latter represented by agricultural, livestock and fish farming activities. These activities have contributed to the contamination observed at present, being an environment...
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| Format: | Online |
| Language: | spa |
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Universidad Pedagógica y Tecnológica de Colombia
2020
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| Online Access: | https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/11467 |
| _version_ | 1801706347350196224 |
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| author | Jaramillo-García, Diego F. Rodríguez-Sosa, Natalia Salazar-Salazar, Marleny Hurtado-Montaño, Carlos A. Rondón-Lagos, Milena |
| author_facet | Jaramillo-García, Diego F. Rodríguez-Sosa, Natalia Salazar-Salazar, Marleny Hurtado-Montaño, Carlos A. Rondón-Lagos, Milena |
| author_sort | Jaramillo-García, Diego F. |
| collection | OJS |
| description | Tota Lake is a water source of great importance at a regional and national level given its environmental and economic value, the latter represented by agricultural, livestock and fish farming activities. These activities have contributed to the contamination observed at present, being an environmental problem in constant rise, where the health, the development of the communities and the ecological processes have been affected. In fact, Lake Tota has been classified as one of the most threatened ecosystems on the planet by the global network of wetlands. Despite the environmental problems posed by the contamination of the Lake, there are very few studies that investigate the genetic damage generated by exposure to the toxic agents present in this basin. In this regard, an optimal biological model for genotoxicity studies is the zebrafish, given its high genetic homology with humans, as well as its capacity for regeneration, adaptation and immune response to high concentrations of chemical compounds such as pesticides. This review focuses on recent reports on Tota Lake contamination and the use of biological models for genotoxicity studies. |
| format | Online |
| id | oai:oai.revistas.uptc.edu.co:article-11467 |
| institution | Revista Ciencia en Desarrollo |
| language | spa |
| publishDate | 2020 |
| publisher | Universidad Pedagógica y Tecnológica de Colombia |
| record_format | ojs |
| spelling | oai:oai.revistas.uptc.edu.co:article-114672021-04-12T16:16:34Z Tota Lake Pollution and Biological Models for Genotoxicity Studies Contaminación del Lago de Tota y Modelos Biológicos para estudios de Genotoxicidad Jaramillo-García, Diego F. Rodríguez-Sosa, Natalia Salazar-Salazar, Marleny Hurtado-Montaño, Carlos A. Rondón-Lagos, Milena Contaminación, Daño citotóxico, Daño genotóxico, Lago de Tota, Modelo biológico, Pez cebra Biological model, Contamination, Cytotoxic damage, Genotoxic damage, Lake Tota, Zebra fish Tota Lake is a water source of great importance at a regional and national level given its environmental and economic value, the latter represented by agricultural, livestock and fish farming activities. These activities have contributed to the contamination observed at present, being an environmental problem in constant rise, where the health, the development of the communities and the ecological processes have been affected. In fact, Lake Tota has been classified as one of the most threatened ecosystems on the planet by the global network of wetlands. Despite the environmental problems posed by the contamination of the Lake, there are very few studies that investigate the genetic damage generated by exposure to the toxic agents present in this basin. In this regard, an optimal biological model for genotoxicity studies is the zebrafish, given its high genetic homology with humans, as well as its capacity for regeneration, adaptation and immune response to high concentrations of chemical compounds such as pesticides. This review focuses on recent reports on Tota Lake contamination and the use of biological models for genotoxicity studies. El Lago de Tota es una fuente hídrica de gran importancia a nivel regional y nacional dado su valor ambiental y económico, este último representado por actividades agrícolas, pecuarias y piscícolas. Estas actividades han contribuido a la contaminación observada en la actualidad, siendo esta una problemática ambiental en constante ascenso, donde la salud, el desarrollo de las comunidades y los procesos ecológicos, se han visto afectados. De hecho, el Lago de Tota ha sido catalogado como uno de los ecosistemas más amenazados del planeta por la red mundial de humedales. A pesar de la problemática ambiental que representa la contaminación del Lago, son muy pocos los estudios que indagan acerca del daño genético generado por la exposición a los agentes tóxicos presentes en esta cuenca. A este respecto un modelo biológico óptimo para estudios de genotoxicidad lo constituye el pez cebra, dada su alta homología genética con el humano, así como su capacidad de regeneración, adaptación y respuesta inmune ante altas concentraciones de compuestos químicos como los plaguicidas. Esta revisión se enfoca en reportes recientes sobre la contaminación del Lago de Tota y en el uso de modelos biológicos para estudios de genotoxicidad. Universidad Pedagógica y Tecnológica de Colombia 2020-07-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/11467 10.19053/01217488.v11.n2.2020.11467 Ciencia En Desarrollo; Vol. 11 No. 2 (2020): Vol 11, Núm.2 (2020): Julio-Diciembre; 65-83 Ciencia en Desarrollo; Vol. 11 Núm. 2 (2020): Vol 11, Núm.2 (2020): Julio-Diciembre; 65-83 2462-7658 0121-7488 spa https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/11467/10298 Derechos de autor 2020 CIENCIA EN DESARROLLO |
| spellingShingle | Contaminación, Daño citotóxico, Daño genotóxico, Lago de Tota, Modelo biológico, Pez cebra Biological model, Contamination, Cytotoxic damage, Genotoxic damage, Lake Tota, Zebra fish Jaramillo-García, Diego F. Rodríguez-Sosa, Natalia Salazar-Salazar, Marleny Hurtado-Montaño, Carlos A. Rondón-Lagos, Milena Tota Lake Pollution and Biological Models for Genotoxicity Studies |
| title | Tota Lake Pollution and Biological Models for Genotoxicity Studies |
| title_alt | Contaminación del Lago de Tota y Modelos Biológicos para estudios de Genotoxicidad |
| title_full | Tota Lake Pollution and Biological Models for Genotoxicity Studies |
| title_fullStr | Tota Lake Pollution and Biological Models for Genotoxicity Studies |
| title_full_unstemmed | Tota Lake Pollution and Biological Models for Genotoxicity Studies |
| title_short | Tota Lake Pollution and Biological Models for Genotoxicity Studies |
| title_sort | tota lake pollution and biological models for genotoxicity studies |
| topic | Contaminación, Daño citotóxico, Daño genotóxico, Lago de Tota, Modelo biológico, Pez cebra Biological model, Contamination, Cytotoxic damage, Genotoxic damage, Lake Tota, Zebra fish |
| topic_facet | Contaminación, Daño citotóxico, Daño genotóxico, Lago de Tota, Modelo biológico, Pez cebra Biological model, Contamination, Cytotoxic damage, Genotoxic damage, Lake Tota, Zebra fish |
| url | https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/11467 |
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