Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement
Biomaterials have become a fundamental tool in tissue engineering and regenerative medicine because of their capacity to mimic the original tissue. Currently, bone cements are being studied as bone substitute biomaterials in different pathologies, also compounds with materials such as hydroxyapatit...
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| Format: | Online |
| Language: | spa |
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Universidad Pedagógica y Tecnológica de Colombia
2022
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| Online Access: | https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018 |
| _version_ | 1801706352814325760 |
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| author | Gárcia-Sánchez, Karen Quiñones, Iber J. Gutierrez-M, Jose Oscar Camargo-Amado, Ruben Basante-Romo, Mónica J. |
| author_facet | Gárcia-Sánchez, Karen Quiñones, Iber J. Gutierrez-M, Jose Oscar Camargo-Amado, Ruben Basante-Romo, Mónica J. |
| author_sort | Gárcia-Sánchez, Karen |
| collection | OJS |
| description |
Biomaterials have become a fundamental tool in tissue engineering and regenerative medicine because of their capacity to mimic the original tissue. Currently, bone cements are being studied as bone substitute biomaterials in different pathologies, also compounds with materials such as hydroxyapatite are analyzed to provide them bioactivity. In the present study, the main goal was to evaluate the bioactive nature of hydroxyapatite samples obtained from eggshells. Hydroxyapatite synthesis was performed by a wet chemical method, in which calcium oxide from eggshells and phosphoric acid were used as sources of calcium and phosphorus, respectively. The chemical characterization carried out by Raman spectroscopy and EDS showed that it was possible to obtain hydroxyapatite from this residue with a Ca/P ratio of 2,187. For the bioactivity study, the powder samples were immersed in simulated body fluid for 14 and 28 days. Before and after the treatment the samples were characterized to determine their Ca/P ratio and behavior over time by Raman spectroscopy, and SEM-EDS microscopy. The characterization techniques allowed us to know that hydroxyapatite synthesized from eggshells had bioactive properties. It is stable material in contact with the simulated body fluid, which suggests it is a great candidate to be used as an addition to conventional bone cement.
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| format | Online |
| id | oai:oai.revistas.uptc.edu.co:article-14018 |
| institution | Revista Ciencia en Desarrollo |
| language | spa |
| publishDate | 2022 |
| publisher | Universidad Pedagógica y Tecnológica de Colombia |
| record_format | ojs |
| spelling | oai:oai.revistas.uptc.edu.co:article-140182023-06-26T20:42:54Z Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement Bioactividad de hidroxiapatita obtenida a partir de cáscara de huevo para uso potencial como cemento óseo Gárcia-Sánchez, Karen Quiñones, Iber J. Gutierrez-M, Jose Oscar Camargo-Amado, Ruben Basante-Romo, Mónica J. Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad. Hydroxyapatite, Biomaterial, Eggshell, Bioactivity. Biomaterials have become a fundamental tool in tissue engineering and regenerative medicine because of their capacity to mimic the original tissue. Currently, bone cements are being studied as bone substitute biomaterials in different pathologies, also compounds with materials such as hydroxyapatite are analyzed to provide them bioactivity. In the present study, the main goal was to evaluate the bioactive nature of hydroxyapatite samples obtained from eggshells. Hydroxyapatite synthesis was performed by a wet chemical method, in which calcium oxide from eggshells and phosphoric acid were used as sources of calcium and phosphorus, respectively. The chemical characterization carried out by Raman spectroscopy and EDS showed that it was possible to obtain hydroxyapatite from this residue with a Ca/P ratio of 2,187. For the bioactivity study, the powder samples were immersed in simulated body fluid for 14 and 28 days. Before and after the treatment the samples were characterized to determine their Ca/P ratio and behavior over time by Raman spectroscopy, and SEM-EDS microscopy. The characterization techniques allowed us to know that hydroxyapatite synthesized from eggshells had bioactive properties. It is stable material in contact with the simulated body fluid, which suggests it is a great candidate to be used as an addition to conventional bone cement. Los biomateriales se han constituido como una herramienta fundamental en la ingeniería de tejidos y la medicina regenerativa, debido a que tratan y en algunos casos logran mimetizar el tejido original. Actualmente se estudian los cementos óseos como biomateriales sustitutos de hueso en diferentes patologías, y se analizan diferentes compuestos con contenido de hidroxiapatita para dotarlos de bioactividad. En el presente estudio se tuvo como objetivo evaluar el carácter bioactivo en muestras de hidroxiapatita obtenida a partir de cáscara de huevo para usarse como posible adición a los cementos óseos. La síntesis de la hidroxiapatita se realizó por el método de precipitación, en la que se usó el óxido de calcio proveniente de las cáscaras de huevo y el ácido fosfórico como fuentes de calcio y fósforo, respectivamente. La caracterización química realizada por medio de espectroscopia Raman y EDS, permitió evidenciar que se logró obtener hidroxiapatita a partir de éste residuo con una relación Ca/P de 2,187. Para el estudio de bioactividad, se sumergieron las muestras en polvo en un fluido biológico simulado durante 14 y 28 días, y con espectroscopia Raman y microscopía SEM-EDS, se caracterizaron las muestras tanto antes como después del tratamiento para determinar su relación Ca/P y comportamiento con el tiempo. Las técnicas de caracterización permitieron determinar que la hidroxiapatita de cáscara de huevo presenta propiedades bioactivas y que además es un material estable al estar en contacto con el fluido biológico simulado, una gran candidata para usarse como adición a los cementos óseos convencionales. Universidad Pedagógica y Tecnológica de Colombia 2022-01-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018 10.19053/01217488.v13.n1.2022.14018 Ciencia En Desarrollo; Vol. 13 No. 1 (2022): Vol. 13 Núm. 1 (2022): Vol 13, Núm.1 (2022): Enero-Junio; 103-114 Ciencia en Desarrollo; Vol. 13 Núm. 1 (2022): Vol. 13 Núm. 1 (2022): Vol 13, Núm.1 (2022): Enero-Junio; 103-114 2462-7658 0121-7488 spa https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018/12526 |
| spellingShingle | Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad. Hydroxyapatite, Biomaterial, Eggshell, Bioactivity. Gárcia-Sánchez, Karen Quiñones, Iber J. Gutierrez-M, Jose Oscar Camargo-Amado, Ruben Basante-Romo, Mónica J. Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| title | Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| title_alt | Bioactividad de hidroxiapatita obtenida a partir de cáscara de huevo para uso potencial como cemento óseo |
| title_full | Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| title_fullStr | Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| title_full_unstemmed | Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| title_short | Bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| title_sort | bioactivity of hydroxyapatite obtained from eggshell for potential use as bone cement |
| topic | Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad. Hydroxyapatite, Biomaterial, Eggshell, Bioactivity. |
| topic_facet | Hidroxiapatita, Biomaterial, Cáscara de huevo, Bioactividad. Hydroxyapatite, Biomaterial, Eggshell, Bioactivity. |
| url | https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/14018 |
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