Immunotherapy in Melanoma: Role of TIGIT and LAG-3 on the antitumor immune microenvironment

Melanoma, is a malignant tumor arising from melanocytes. Given the ability of melanoma cells to inactivate lymphocytes, immunotherapy in melanoma has focused on using immune checkpoint inhibitors (ICIs) to counteract immune evasion. The lymphocyte activation gene 3 (LAG-3) and the inhibitory recepto...

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Bibliographic Details

Main Authors:	Gaona Neira, Geidi Catherinne, Salazar Prieto, Shanon Daniela, Rondón Lagos, Sandra Milena
Format:	Online
Language:	spa
Published:	Universidad Pedagógica y Tecnológica de Colombia 2023
Subjects:	Anticuerpos monoclonales Terapia antitumoral combinada punto de control inmunitario LAG-3 TIGIT células T Monoclonal antibodies T cells immune checkpoint combined antitumor therapy
Online Access:	https://revistas.uptc.edu.co/index.php/ciencia_en_desarrollo/article/view/15041