Antibacterial properties of ethanolic extracts from Melochia pyramidata L.
This study investigates the antibacterial properties of ethanolic extracts from the weed Melochia pyramidata L. Through gas chromatography-mass spectrometry (GC-MS) analysis, several compounds were identified, including pyranones, phenolic compounds, terpenes, coumarin, aryl-tetrahydrofurans, and ph...
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Sociedad Colombiana de Ciencias Hortícolas-SCCH and Universidad Pedagógica y Tecnológica de Colombia-UPTC
2024
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| Online Access: | https://revistas.uptc.edu.co/index.php/ciencias_horticolas/article/view/16252 |
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| author | Carrillo, María Fernanda Ortiz-Rojas, Luz Yineth Chaves-Bedoya, Giovanni |
| author_facet | Carrillo, María Fernanda Ortiz-Rojas, Luz Yineth Chaves-Bedoya, Giovanni |
| author_sort | Carrillo, María Fernanda |
| collection | OJS |
| description | This study investigates the antibacterial properties of ethanolic extracts from the weed Melochia pyramidata L. Through gas chromatography-mass spectrometry (GC-MS) analysis, several compounds were identified, including pyranones, phenolic compounds, terpenes, coumarin, aryl-tetrahydrofurans, and phenylpropanoids. Among the most abundant compounds were 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one and palmitic acid. Although several known metabolites were identified, the main focus was on evaluating the antibacterial capacity of the complete extract. The study's findings indicate that the ethanolic extract exhibits substantial inhibition against various bacteria. Specifically, Gram-positive S. aureus showed the greatest sensitivity to the extract, with an average inhibition zone of 13.12 mm, followed by E. coli with an average inhibition of 10.95 mm. These findings suggest that the M. pyramidata extract could be a promising source for the development of antimicrobial agents. However, it is emphasized that the tests were conducted in vitro, and further research is needed to confirm the efficacy of the extract in clinical in vivo applications. This study highlights the importance of evaluating underexplored natural resources like weeds in the search for antimicrobial solutions and contributes to the understanding of the potential of M. pyramidata in antibacterial research. |
| format | Online |
| id | oai:oai.revistas.uptc.edu.co:article-16252 |
| institution | Revista Colombiana de Ciencias Hortícolas |
| language | eng |
| publishDate | 2024 |
| publisher | Sociedad Colombiana de Ciencias Hortícolas-SCCH and Universidad Pedagógica y Tecnológica de Colombia-UPTC |
| record_format | ojs |
| spelling | oai:oai.revistas.uptc.edu.co:article-162522024-06-11T12:49:18Z Antibacterial properties of ethanolic extracts from Melochia pyramidata L. Propiedades antibacterianas de los extractos etanólicos de Melochia pyramidata L. Carrillo, María Fernanda Ortiz-Rojas, Luz Yineth Chaves-Bedoya, Giovanni Secondary metabolites bioactivity Weed-derived compounds Plant extracts Pathogenic bacteria Phytochemistry Metabolitos secundarios Bioactividad Compuestos derivados de arvenses Extractos vegetales Bacterias patogénicas Fitoquímica This study investigates the antibacterial properties of ethanolic extracts from the weed Melochia pyramidata L. Through gas chromatography-mass spectrometry (GC-MS) analysis, several compounds were identified, including pyranones, phenolic compounds, terpenes, coumarin, aryl-tetrahydrofurans, and phenylpropanoids. Among the most abundant compounds were 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one and palmitic acid. Although several known metabolites were identified, the main focus was on evaluating the antibacterial capacity of the complete extract. The study's findings indicate that the ethanolic extract exhibits substantial inhibition against various bacteria. Specifically, Gram-positive S. aureus showed the greatest sensitivity to the extract, with an average inhibition zone of 13.12 mm, followed by E. coli with an average inhibition of 10.95 mm. These findings suggest that the M. pyramidata extract could be a promising source for the development of antimicrobial agents. However, it is emphasized that the tests were conducted in vitro, and further research is needed to confirm the efficacy of the extract in clinical in vivo applications. This study highlights the importance of evaluating underexplored natural resources like weeds in the search for antimicrobial solutions and contributes to the understanding of the potential of M. pyramidata in antibacterial research. Este estudio investiga las propiedades antibacterianas de extractos etanólicos de la maleza Melochia pyramidata L. A través del análisis de cromatografía de gases acoplada a espectrometría de masas (GC-MS), se identificaron varios compuestos, incluyendo piranonas, compuestos fenólicos, terpenos, cumarina, aril-tetrahidrofuranos y fenilpropanoides. Entre los compuestos más abundantes se encontraron la 3,5-dihidroxi-6-metil-2,3-dihidro-4H-piran-4-ona y el ácido palmítico. Aunque se identificaron varios metabolitos conocidos, el enfoque principal se centró en la evaluación de la capacidad antibacteriana del extracto completo. Los resultados del estudio indican que el extracto etanólico exhibe una inhibición sustancial contra varias bacterias. Específicamente, S. aureus, una bacteria Gram-positiva, mostró la mayor sensibilidad al extracto, con una zona media de inhibición de 13,12 mm, seguido por E. coli con una inhibición media de 10,95 mm. Estos hallazgos sugieren que el extracto de M. pyramidata podría ser una fuente prometedora para el desarrollo de agentes antimicrobianos. Sin embargo, se destaca que las pruebas se realizaron in vitro, y es necesario realizar más investigaciones para confirmar la eficacia del extracto en aplicaciones clínicas in vivo. Este estudio recalca la importancia de evaluar recursos naturales sub explorados como las malezas en la búsqueda de soluciones antimicrobianas y aporta a la comprensión del potencial de M. pyramidata en la investigación antibacteriana. Sociedad Colombiana de Ciencias Hortícolas-SCCH and Universidad Pedagógica y Tecnológica de Colombia-UPTC 2024-01-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Text Texto application/pdf https://revistas.uptc.edu.co/index.php/ciencias_horticolas/article/view/16252 10.17584/rcch.2024v18i1.16252 Revista Colombiana de Ciencias Hortícolas; Vol. 18 No. 1 (2024); e16252 Revista Colombiana de Ciencias Hortícolas; Vol. 18 Núm. 1 (2024); e16252 Revista Colombiana de Ciencias Hortícolas; Vol. 18 No 1 (2024); e16252 Revista Colombiana de Ciencias Hortícolas; V. 18 N. 1 (2024); e16252 Revista Colombiana de Ciencias Hortícolas; v. 18 n. 1 (2024); e16252 2422-3719 2011-2173 eng https://revistas.uptc.edu.co/index.php/ciencias_horticolas/article/view/16252/13913 Colombia; Norte de Santanter, Cucuta Colombia; Norte de Santanter, Cúcuta Copyright (c) 2024 Revista Colombiana de Ciencias Hortícolas http://creativecommons.org/licenses/by-nc-sa/4.0 |
| spellingShingle | Secondary metabolites bioactivity Weed-derived compounds Plant extracts Pathogenic bacteria Phytochemistry Metabolitos secundarios Bioactividad Compuestos derivados de arvenses Extractos vegetales Bacterias patogénicas Fitoquímica Carrillo, María Fernanda Ortiz-Rojas, Luz Yineth Chaves-Bedoya, Giovanni Antibacterial properties of ethanolic extracts from Melochia pyramidata L. |
| title | Antibacterial properties of ethanolic extracts from Melochia pyramidata L. |
| title_alt | Propiedades antibacterianas de los extractos etanólicos de Melochia pyramidata L. |
| title_full | Antibacterial properties of ethanolic extracts from Melochia pyramidata L. |
| title_fullStr | Antibacterial properties of ethanolic extracts from Melochia pyramidata L. |
| title_full_unstemmed | Antibacterial properties of ethanolic extracts from Melochia pyramidata L. |
| title_short | Antibacterial properties of ethanolic extracts from Melochia pyramidata L. |
| title_sort | antibacterial properties of ethanolic extracts from melochia pyramidata l |
| topic | Secondary metabolites bioactivity Weed-derived compounds Plant extracts Pathogenic bacteria Phytochemistry Metabolitos secundarios Bioactividad Compuestos derivados de arvenses Extractos vegetales Bacterias patogénicas Fitoquímica |
| topic_facet | Secondary metabolites bioactivity Weed-derived compounds Plant extracts Pathogenic bacteria Phytochemistry Metabolitos secundarios Bioactividad Compuestos derivados de arvenses Extractos vegetales Bacterias patogénicas Fitoquímica |
| url | https://revistas.uptc.edu.co/index.php/ciencias_horticolas/article/view/16252 |
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