Diagnosis of canine monocytotropic ehrlichiosis: an update review

Canine monocytic ehrlichiosis (CME) is caused by the infection with a rickettsial organism, Ehrlichia canis. This organism is replicated only in the cytoplasm of blood monocytes and tissue macrophages. CME has been reported throughout the world but at higher frequencies in tropical and subtropical r...

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Main Authors: Rodríguez-Vivas, Roger Iván, Bolio-González, Manuel Emilio, Ojeda-Chi, Melina Maribel
Format: Online
Language:spa
Published: Universidad Pedagógica y Tecnológica de Colombia 2015
Subjects:
Online Access:https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/4126
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author Rodríguez-Vivas, Roger Iván
Bolio-González, Manuel Emilio
Ojeda-Chi, Melina Maribel
author_facet Rodríguez-Vivas, Roger Iván
Bolio-González, Manuel Emilio
Ojeda-Chi, Melina Maribel
author_sort Rodríguez-Vivas, Roger Iván
collection OJS
description Canine monocytic ehrlichiosis (CME) is caused by the infection with a rickettsial organism, Ehrlichia canis. This organism is replicated only in the cytoplasm of blood monocytes and tissue macrophages. CME has been reported throughout the world but at higher frequencies in tropical and subtropical regions. CME is often under-recognized since the disease is difficult to diagnose due to variable clinical signs, its different stages, and frequent co—infection with other tick-borne pathogens or other infectious agents. Clinical manifestations and the traditional diagnostic techniques such as hematology and demonstration of typical cytoplasmic E. canis-morulae in monocytes in blood smears have been used for the diagnosis of CME; however, the PCR—based diagnostic tests and serology methods based on specific antigens, are the most sensitive and specific for this disease. This article reviews the current literature covering the diagnosis of infection by E. canis in dogs.
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spelling oai:oai.revistas.uptc.edu.co:article-41262018-11-21T00:12:05Z Diagnosis of canine monocytotropic ehrlichiosis: an update review Diagnóstico de la ehrlichiosis monocítica canina: una revisión actualizada Rodríguez-Vivas, Roger Iván Bolio-González, Manuel Emilio Ojeda-Chi, Melina Maribel ehrlichia canis dogs diseases thrombocytopenia molecular diagnostic techniques Inmuneadsortion Enzimatic test. Ehrlichia canis Enfermedades caninas Trombocitopenia Diagnóstico molecular Ensayo de Inmunoadsorción Enzimática Canine monocytic ehrlichiosis (CME) is caused by the infection with a rickettsial organism, Ehrlichia canis. This organism is replicated only in the cytoplasm of blood monocytes and tissue macrophages. CME has been reported throughout the world but at higher frequencies in tropical and subtropical regions. CME is often under-recognized since the disease is difficult to diagnose due to variable clinical signs, its different stages, and frequent co—infection with other tick-borne pathogens or other infectious agents. Clinical manifestations and the traditional diagnostic techniques such as hematology and demonstration of typical cytoplasmic E. canis-morulae in monocytes in blood smears have been used for the diagnosis of CME; however, the PCR—based diagnostic tests and serology methods based on specific antigens, are the most sensitive and specific for this disease. This article reviews the current literature covering the diagnosis of infection by E. canis in dogs. La ehrlichiosis monocítica canina (EMC) es causada por la infección de una rickettsia denominada Ehrlichia canis, este microorganismo se reproduce solamente en el citoplasma de los monocitos sanguíneos y macrófagos tisulares. La EMC ha sido reportada en todo el mundo, pero las frecuencias más altas se reportan en las regiones tropicales y subtropicales. La EMC no siempre es reconocida clínicamente, pues es difícil de diagnosticar debido a que los signos clínicos son variables, a que se presenta en diferentes fases y a la existencia de coinfecciones con otros patógenos transmitidos por garrapatas y otros agentes infecciosos. Las manifestaciones clínicas y las técnicas de diagnóstico tradicionales, como el diagnóstico hematológico y la demostración típica de mórulas de E. canis en el citoplasma de monocitos en frotis sanguíneos, se han utilizado para el diagnóstico de la EMC, sin embargo, las pruebas de diagnóstico por PCR y la serología mediante el uso de antígenos específicos son las pruebas más sensibles y específicas para el diagnóstico de la enfermedad. Este artículo presenta una revisión actualizada sobre el diagnóstico de la infección por E. canis en perros. Universidad Pedagógica y Tecnológica de Colombia 2015-01-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion investigation application/pdf https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/4126 10.19053/01228420.4126 Ciencia y Agricultura; Vol. 12 No. 1 (2015); 83-96 Ciencia y Agricultura; Vol. 12 Núm. 1 (2015); 83-96 2539-0899 spa https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/4126/3565 Copyright (c) 2016 CIENCIA Y AGRICULTURA
spellingShingle ehrlichia canis
dogs diseases
thrombocytopenia
molecular diagnostic techniques
Inmuneadsortion Enzimatic test.
Ehrlichia canis
Enfermedades caninas
Trombocitopenia
Diagnóstico molecular
Ensayo de Inmunoadsorción Enzimática
Rodríguez-Vivas, Roger Iván
Bolio-González, Manuel Emilio
Ojeda-Chi, Melina Maribel
Diagnosis of canine monocytotropic ehrlichiosis: an update review
title Diagnosis of canine monocytotropic ehrlichiosis: an update review
title_alt Diagnóstico de la ehrlichiosis monocítica canina: una revisión actualizada
title_full Diagnosis of canine monocytotropic ehrlichiosis: an update review
title_fullStr Diagnosis of canine monocytotropic ehrlichiosis: an update review
title_full_unstemmed Diagnosis of canine monocytotropic ehrlichiosis: an update review
title_short Diagnosis of canine monocytotropic ehrlichiosis: an update review
title_sort diagnosis of canine monocytotropic ehrlichiosis an update review
topic ehrlichia canis
dogs diseases
thrombocytopenia
molecular diagnostic techniques
Inmuneadsortion Enzimatic test.
Ehrlichia canis
Enfermedades caninas
Trombocitopenia
Diagnóstico molecular
Ensayo de Inmunoadsorción Enzimática
topic_facet ehrlichia canis
dogs diseases
thrombocytopenia
molecular diagnostic techniques
Inmuneadsortion Enzimatic test.
Ehrlichia canis
Enfermedades caninas
Trombocitopenia
Diagnóstico molecular
Ensayo de Inmunoadsorción Enzimática
url https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/4126
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